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D-Glucose, o-[n-(2-Hydroxyacetyl)-α-Neuraminosyl]-(2→3)-o-β-D-Galactopyranosyl-(1→4)- CAS NO 81275-44-7


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CAS No.:81275-44-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Glucose, o-[n-(2-Hydroxyacetyl)-α-Neuraminosyl]-(2→3)-o-β-D-Galactopyranosyl-(1→4)- is a complex, high-purity oligosaccharide derivative, specifically a sialylated lactose structure. This compound is of significant value as a critical biochemical tool and a potential building block for advanced glycobiology research and biopharmaceutical development. It is primarily required by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for applications in glycan synthesis, receptor-ligand interaction studies, and the development of novel therapeutics and vaccines.

Application

  • Glycobiology Research: Used as a standard or intermediate in the study of carbohydrate-protein interactions, cell signaling, and glycan biosynthesis pathways.
  • Pharmaceutical Development: Serves as a key starting material or reference compound for synthesizing complex glycoconjugates, including potential drug candidates and vaccine components.
  • Diagnostic Reagent Production: Employed in the development of diagnostic kits and assays that detect specific carbohydrate-binding proteins or antibodies.
  • Enzymology Studies: Acts as a substrate for studying the activity and specificity of glycosyltransferases, neuraminidases, and other carbohydrate-active enzymes.
  • Biomimetic Material Synthesis: Utilized in creating synthetic glycopolymers or surfaces that mimic natural cell membranes for biomedical applications.
  • Nutritional Science Research: Investigated for its role as a specialized human milk oligosaccharide (HMO) analog, relevant to infant nutrition and gut health studies.

Basic Information

Product Name D-Glucose, o-[n-(2-Hydroxyacetyl)-α-Neuraminosyl]-(2→3)-o-β-D-Galactopyranosyl-(1→4)-
CAS No. 81275-44-7
Molecular Formula C25H41NO20
Molecular Weight 675.60 g/mol
Synonyms 3'-Sialyllactose (N-Glycolylneuraminic acid); Lacto-N-neotetraose I derivative; N-Glycolylneuraminyl-α-(2→3)-lactose; α-Neu5Gc-(2→3)-β-D-Gal-(1→4)-D-Glc; Sialyl-lactose (NGNA); 3'-SL (NGNA); 3'-N-Glycolylneuraminyllactose; O-(5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosylonate)-(2→3)-O-β-D-galactopyranosyl-(1→4)-D-glucopyranose (N-Glycolyl form)
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Quality Control

Our D-Glucose, o-[n-(2-Hydroxyacetyl)-α-Neuraminosyl]-(2→3)-o-β-D-Galactopyranosyl-(1→4)- is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation and NMR for structural verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to reference spectrum
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 1.0%
Bacterial Endotoxins < 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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