Description

((R)-8-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Propyl-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in advanced organic synthesis. Its defined stereochemistry and functionalized tetralin scaffold make it an invaluable intermediate for creating enantiomerically pure compounds. This product is essential for research and development in the pharmaceutical industry, particularly for the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential CNS-active drugs and receptor modulators.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically enriched compounds.
• Medicinal Chemistry Research: Serves as a core structural motif for constructing compound libraries in drug discovery programs focused on GPCR targets.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up synthetic routes for candidate drugs during pre-clinical and clinical development phases.

Basic Information

Product Name	((R)-8-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Propyl-Amine Hydrochloride
CAS No.	81185-23-1
Molecular Formula	C14H22ClNO
Molecular Weight	255.78 g/mol
Synonyms	(R)-8-Methoxy-1,2,3,4-tetrahydro-2-naphthalenepropanamine hydrochloride; (R)-2-(3-Aminopropyl)-8-methoxy-1,2,3,4-tetrahydronaphthalene hydrochloride; (R)-8-Methoxy-1,2,3,4-tetrahydro-2-naphthylpropylamine HCl; (R)-Naphthalen-2-yl-propyl-amine hydrochloride; (R)-8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl-propylamine HCl; (R)-TPA Hydrochloride; (R)-2-(3-Aminopropyl)-8-methoxytetralin hydrochloride
EINECS	Contact for details

Quality Control

Our ((R)-8-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Propyl-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.