Description

n-(2,5-Difluoro-Phenyl)-Formamide is a specialized aromatic formamide derivative characterized by its difluoro-substituted phenyl ring. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes.
• Organic Synthesis Reagent: Versatile reagent for constructing complex heterocyclic compounds and facilitating amide bond formation in medicinal chemistry.
• Polymer Modification: Intermediate for introducing fluorine-containing functional groups into polymers to alter thermal and chemical resistance properties.
• Chemical Research & Development: Standard reference compound and starting material in academic and industrial R&D laboratories for novel chemical entity discovery.

Basic Information

Product Name	n-(2,5-Difluoro-Phenyl)-Formamide
CAS No.	81183-56-4
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	2,5-Difluorophenylformamide; N-(2,5-Difluorophenyl)formamide; Formamide, N-(2,5-difluorophenyl)-; 2,5-Difluoroaniline-N-carboxaldehyde; 2,5-Difluorobenzeneformamide; 2,5-Difluoro-N-formylaniline; 81183-56-4
EINECS	Contact for details

Quality Control

Our n-(2,5-Difluoro-Phenyl)-Formamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. Certificates of Analysis (COA) with complete batch-specific data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.