Description

(1R,2R,5R)-2-(2-Hydroxypropan-2-Yl)-5-Methyl-Cyclohexan-1-Ol is a high-purity, stereochemically defined tertiary alcohol and diol derivative of menthol. This compound matters as a versatile chiral building block and intermediate for the synthesis of complex organic molecules, offering precise stereochemical control. It is needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fragrance sectors for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is critical for bioactivity.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthesizing novel terpene-based aroma chemicals and flavor compounds with unique sensory profiles.
• Asymmetric Catalysis: Employed as a chiral ligand or auxiliary in catalytic processes to induce enantioselectivity in synthetic transformations.
• Material Science Research: Investigated as a monomer or modifying agent for creating polymers with specific tacticity and physical properties.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1R,2R,5R)-2-(2-Hydroxypropan-2-Yl)-5-Methyl-Cyclohexan-1-Ol
CAS No.	81176-88-7
Molecular Formula	C10H20O2
Molecular Weight	172.26 g/mol
Synonyms	(1R,2R,5R)-2-(2-Hydroxy-2-propyl)-5-methylcyclohexanol; (1R,2R,5R)-2-(2-Hydroxypropan-2-yl)-5-methylcyclohexan-1-ol; 8-Hydroxy-p-menthan-3-ol; Dihydroisopulegol, 8-hydroxy-; (1R,2R,5R)-8-Hydroxy-p-menthan-3-ol; (1R,2R,5R)-2-(1-Hydroxy-1-methylethyl)-5-methylcyclohexanol
EINECS	Contact for details

Quality Control

Our (1R,2R,5R)-2-(2-Hydroxypropan-2-Yl)-5-Methyl-Cyclohexan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.