Description

1H-Indazole-6-Carboxylic Acid, 5-Amino- is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its dual functional groups—an amino and a carboxylic acid—which enable versatile derivatization for creating complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indazole core.
• Ligand Synthesis: Serves as a versatile scaffold for creating chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of advanced polymers and organic electronic materials.
• Bioconjugation: The carboxylic acid group facilitates coupling reactions for labeling proteins or other biomolecules in diagnostic assay development.
• Chemical Biology Probe Development: Utilized as a core structure for designing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	1H-Indazole-6-Carboxylic Acid, 5-Amino-
CAS No.	81115-49-3
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	5-Amino-1H-indazole-6-carboxylic acid; 5-Aminoindazole-6-carboxylic Acid; 6-Carboxy-5-aminoindazole; 5-Amino-6-indazolecarboxylic Acid; 1H-Indazole-6-carboxylic acid, 5-amino-; 5-Amino-1H-indazole-6-carboxylic acid; 81115-49-3; 5-Aminoindazole-6-CA
EINECS	Contact for details

Quality Control

Our 1H-Indazole-6-Carboxylic Acid, 5-Amino- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.