Description

Glycine, n-(2-Mercapto-1-Oxopropyl)-, Ethyl Ester is a specialized organic compound featuring a unique thiol-functionalized glycine backbone, making it a valuable building block in advanced chemical synthesis. Its molecular structure, which combines ester, amide, and thiol groups, provides versatile reactivity for creating complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel biochemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring thiol or disulfide linkages for bioactivity.
• Peptide Synthesis: Used as a modified amino acid derivative for introducing mercapto-functionalized side chains into custom peptides and peptidomimetics.
• Bioconjugation Chemistry: Serves as a versatile linker or handle for attaching labels, drugs, or other functional groups to proteins, antibodies, or nanoparticles via thiol-reactive chemistry.
• Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating novel chemical entities in medicinal chemistry programs.
• Fine Chemical Production: Acts as a building block for synthesizing specialty chemicals, catalysts, and ligands used in asymmetric synthesis.

Basic Information

Product Name	Glycine, n-(2-Mercapto-1-Oxopropyl)-, Ethyl Ester
CAS No.	81075-15-2
Molecular Formula	C7H13NO3S
Molecular Weight	191.25 g/mol
Synonyms	N-(2-Mercapto-1-oxopropyl)glycine ethyl ester; Ethyl 2-[(2-mercaptopropanoyl)amino]acetate; Glycine, N-(2-mercapto-1-oxopropyl)-, ethyl ester; 2-[(2-Mercaptopropanoyl)amino]acetic Acid Ethyl Ester; N-(2-Mercaptopropionyl)glycine Ethyl Ester; Thiol-functionalized glycine ethyl ester; Mercaptopropionylglycine ethyl ester
EINECS	Contact for details

Quality Control

Our Glycine, n-(2-Mercapto-1-Oxopropyl)-, Ethyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and titration to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be opaque or stored in dark conditions. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.