Description

4-Bromo-Alpha,Alpha,α-Trifluoro-o-Toluidine Hydrochloride, 98 is a high-purity halogenated aniline derivative, specifically the hydrochloride salt of a trifluoromethyl- and bromo-substituted toluidine. This compound is a critical pharmaceutical intermediate and advanced organic building block valued for its unique combination of fluorine and bromine atoms, which are essential for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily required by research institutions and fine chemical manufacturers engaged in the development of agrochemicals, specialty dyes, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, leveraging the fluorine and bromine substituents for enhanced efficacy.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the 4-bromo-2-(trifluoromethyl)aniline moiety into complex organic frameworks via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where halogenated aromatic units are required.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast halogenated dyes.

Basic Information

Product Name	4-Bromo-Alpha,Alpha,α-Trifluoro-o-Toluidine Hydrochloride, 98
CAS No.	80997-89-3
Molecular Formula	C8H6BrClF3N
Molecular Weight	294.49 g/mol
Synonyms	4-Bromo-2-(trifluoromethyl)aniline hydrochloride; 2-Amino-5-bromo-α,α,α-trifluorotoluene hydrochloride; 5-Bromo-α,α,α-trifluoro-o-toluidine hydrochloride; 4-Bromo-α,α,α-trifluoro-o-toluidine HCl; 4-Bromo-2-trifluoromethylaniline hydrochloride; 5-Bromo-2-(trifluoromethyl)aniline hydrochloride; 4-Bromo-α,α,α-trifluoro-2-methylaniline hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-Alpha,Alpha,α-Trifluoro-o-Toluidine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure the specified purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.