Description

Boc-Tyr(Ac)-Oh CAS NO 80971-82-0 is a protected amino acid derivative, specifically N-α-tert-butoxycarbonyl-O-acetyl-L-tyrosine, widely used as a crucial building block in peptide synthesis. Its value lies in providing orthogonal protection for the tyrosine side chain hydroxyl group and the α-amino group, enabling precise and sequential coupling in complex peptide assembly. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected tyrosine derivative for the automated synthesis of complex peptide sequences.
• Solution-Phase Peptide Synthesis: Used in the classical synthesis of peptides, particularly for segments requiring selective deprotection.
• Pharmaceutical Intermediates: Serves as a critical raw material in the production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Research & Development: Employed in academic and industrial R&D for studying protein structure-function relationships and developing novel bioactive peptides.
• Bioconjugation: The protected tyrosine can be used to introduce specific functional handles into peptides for labeling or coupling with other molecules.
• Combinatorial Chemistry: Utilized in libraries for high-throughput screening to discover new lead compounds with therapeutic potential.

Basic Information

Product Name	Boc-Tyr(Ac)-Oh
CAS No.	80971-82-0
Molecular Formula	C₁₆H₂₁NO₆
Molecular Weight	323.34 g/mol
Synonyms	N-α-tert-Butoxycarbonyl-O-acetyl-L-tyrosine; Boc-L-Tyrosine(Ac)-OH; Boc-Tyr(OAc)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(4-acetyloxyphenyl)propanoic acid; tert-Butoxycarbonyl-O-acetyl-L-tyrosine; N-Boc-O-acetyl-L-tyrosine; Boc-Tyr(Ac)-OH; BOC-TYR(OAC)-OH
EINECS	Contact for details

Quality Control

Our Boc-Tyr(Ac)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for peptide synthesis. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and other relevant physicochemical analyses. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.