Description

(E)-4-(2-Nitrophenyl)-4-Oxo-2-Butenoic Acid is a specialized organic intermediate featuring a conjugated α,β-unsaturated ketone (enone) moiety attached to a 2-nitrophenyl group. This compound is valued for its unique molecular architecture, which makes it a versatile building block in synthetic organic chemistry, particularly for constructing complex heterocyclic systems and functionalized aromatic compounds. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex molecules with potential biological activity, serving as a scaffold for drug discovery and development.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its reactive enone and nitroaromatic functionalities.
• Organic Synthesis Building Block: Employed in cyclization reactions (e.g., Michael additions, cyclocondensations) to construct quinoline, isoquinoline, and other nitrogen-containing heterocycles.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers and functional organic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(E)-4-(2-Nitrophenyl)-4-Oxo-2-Butenoic Acid
CAS No.	80937-24-2
Molecular Formula	C10H7NO5
Molecular Weight	221.17 g/mol
Synonyms	(E)-4-(2-Nitrophenyl)-4-oxobut-2-enoic acid; 4-(2-Nitrophenyl)-4-oxo-2-butenoic acid; 2-Butenoic acid, 4-(2-nitrophenyl)-4-oxo-, (E)-; 4-Oxo-4-(2-nitrophenyl)-2-butenoic acid; (E)-4-(2-Nitrobenzoyl)acrylic acid; 2-Nitrophenyl vinyl ketone carboxylic acid; β-(2-Nitrobenzoyl)acrylic acid
EINECS	Contact for details

Quality Control

Our production of (E)-4-(2-Nitrophenyl)-4-Oxo-2-Butenoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.