Description

2(1H)-Quinolinone, 3,4-Dihydro-1-Methyl-6-(1-Oxo-3-(4-Phenyl-1-Piperazinyl)Propyl)-, Ethanedioate (1:1) is a high-purity, complex organic compound primarily utilized as a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the research and development of novel therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug discovery. Pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers are the primary industries that need this specialized chemical building block to support their innovative pipeline projects.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for neurological and psychiatric applications.
• Chemical Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the design of new bioactive molecules.
• Biochemical Research: Employed in studies investigating specific enzyme inhibition or receptor binding activities.
• Process Development: Used in scaling up and optimizing synthetic routes for the production of target compounds in pilot and commercial scales.

Basic Information

Product Name	2(1H)-Quinolinone, 3,4-Dihydro-1-Methyl-6-(1-Oxo-3-(4-Phenyl-1-Piperazinyl)Propyl)-, Ethanedioate (1:1)
CAS No.	80845-35-8
Molecular Formula	C25H29N3O5
Molecular Weight	451.52 g/mol
Synonyms	1-Methyl-6-[1-oxo-3-(4-phenyl-1-piperazinyl)propyl]-3,4-dihydro-2(1H)-quinolinone ethanedioate; 6-[3-(4-Phenylpiperazin-1-yl)propanoyl]-1-methyl-3,4-dihydroquinolin-2(1H)-one oxalate; 1-Methyl-6-(1-oxo-3-(4-phenyl-1-piperazinyl)propyl)-3,4-dihydro-2(1H)-quinolinone oxalate salt; Oxalic acid salt of 1-methyl-6-[3-(4-phenylpiperazin-1-yl)propanoyl]-3,4-dihydroquinolin-2(1H)-one; 80845-35-8; Quinolinone derivative oxalate salt; Pharmaceutical intermediate 80845-35-8.
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinolinone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.