Description

2(1H)-Quinolinone, 3,4-Dihydro-6-(3-(4-(3-Chlorophenyl)-1-Piperazinyl)-1-Propenyl)- is a high-purity, synthetically derived organic compound featuring a quinolinone core linked to a substituted piperazine moiety. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with optimized biological activity.
• Preclinical Development: Serves as a critical starting material or intermediate in the scale-up synthesis of compounds for preclinical testing.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Chemical Biology Probe: Utilized in research to study biological pathways and protein interactions due to its specific pharmacophore.

Basic Information

Item	Details
Product Name	2(1H)-Quinolinone, 3,4-Dihydro-6-(3-(4-(3-Chlorophenyl)-1-Piperazinyl)-1-Propenyl)-
CAS No.	80834-55-5
Molecular Formula	C22H24ClN3O
Molecular Weight	381.90 g/mol
Synonyms	6-[(E)-3-[4-(3-Chlorophenyl)piperazin-1-yl]prop-1-en-1-yl]-3,4-dihydro-1H-quinolin-2-one; 3,4-Dihydro-6-[3-[4-(3-chlorophenyl)-1-piperazinyl]-1-propenyl]-2(1H)-quinolinone; Aripiprazole Intermediate; OPC-14597 Intermediate; 80834-55-5; 6-(3-(4-(3-Chlorophenyl)piperazin-1-yl)prop-1-en-1-yl)-3,4-dihydroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.