Description

Ethyl 2-Methyl-5-Oxo-5,6-Dihydro[1,6]Naphthyridine-3-Carboxylate is a high-purity organic intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a key building block for the development of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. This compound is essential for research institutions and manufacturers engaged in the development of novel drug candidates, where precise chemical structure and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those containing the [1,6]naphthyridine core.
• API Synthesis: Serves as a key building block for the manufacture of Active Pharmaceutical Ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in research and development (R&D) for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Organic Synthesis Building Block: Utilized in academic and industrial organic synthesis for constructing complex polyheterocyclic systems.

Basic Information

Product Name	Ethyl 2-Methyl-5-Oxo-5,6-Dihydro[1,6]Naphthyridine-3-Carboxylate
CAS No.	80812-55-1
Molecular Formula	C₁₂H₁₂N₂O₃
Molecular Weight	232.24 g/mol
Synonyms	Ethyl 2-methyl-5-oxo-5,6-dihydro-1,6-naphthyridine-3-carboxylate; 3-Carbethoxy-2-methyl-5,6-dihydro-5-oxo-1,6-naphthyridine; 1,6-Naphthyridine-3-carboxylic acid, 5,6-dihydro-2-methyl-5-oxo-, ethyl ester; Ethyl 2-methyl-5-oxo-5,6-dihydro[1,6]naphthyridine-3-carboxylate; 80812-55-1
EINECS	Contact for details

Quality Control

Our Ethyl 2-Methyl-5-Oxo-5,6-Dihydro[1,6]Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.