Description

(1-Amino-2-Phenylethyl)Phosphinic Acid is a specialized organophosphorus compound featuring both amino and phosphinic acid functional groups on a phenethyl backbone. This unique structure makes it a valuable chiral building block and intermediate in advanced synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules, including potential enzyme inhibitors and metal-chelating agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for creating molecules with specific stereochemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal complexation studies due to its phosphinic acid moiety.
• Chemical Research: Acts as a building block in organic synthesis for constructing complex molecules with amino acid-like properties.
• Bioconjugation Chemistry: Potential use in modifying biomolecules or surfaces where its functional groups allow for specific covalent attachment.

Basic Information

Product Name	(1-Amino-2-Phenylethyl)Phosphinic Acid
CAS No.	80744-66-7
Molecular Formula	C8H12NO2P
Molecular Weight	185.16 g/mol
Synonyms	2-Amino-2-phenylethylphosphinic acid; (2-Amino-2-phenylethyl)phosphinic acid; α-Aminobenzeneethanephosphinic acid; 1-Amino-2-phenylethane phosphinic acid; (1-Amino-2-phenylethyl)phosphonic acid (common misnomer); APPA; Phenethylamine phosphinic acid derivative
EINECS	Contact for details

Quality Control

Our (1-Amino-2-Phenylethyl)Phosphinic Acid is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral integrity assessment. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.