Description

7-(Hydroxymethyl)-12-Methylbenz(A)Anthracene Sulfate Ester is a high-purity, synthetically derived polycyclic aromatic hydrocarbon (PAH) derivative, specifically engineered for advanced research and development applications. This compound is critical for scientists requiring precise and reliable reference materials in analytical chemistry and toxicological studies. It serves as a key intermediate and standard for researchers in pharmaceutical development, environmental analysis, and chemical carcinogenesis research, where the study of sulfate ester metabolites is paramount.

Application

• Biochemical Research: Used as a reference standard in the study of metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology & Carcinogenesis Studies: Serves as a crucial metabolite standard for investigating the DNA-binding properties and mutagenic potential of benz(a)anthracene derivatives.
• Analytical Chemistry: Employed as a high-purity calibration standard in HPLC, GC-MS, and LC-MS methods for the quantification of PAH metabolites in complex matrices.
• Pharmaceutical Development: Acts as a synthetic intermediate or a metabolite analog in the development and testing of chemopreventive agents and detoxification pathway modulators.
• Environmental Monitoring: Utilized in method development for detecting and quantifying sulfate-conjugated PAH metabolites in environmental and biological samples.

Basic Information

Product Name	7-(Hydroxymethyl)-12-Methylbenz(A)Anthracene Sulfate Ester
CAS No.	80733-96-6
Molecular Formula	C21H16O4S
Molecular Weight	364.41 g/mol
Synonyms	7-(Hydroxymethyl)-12-methylbenz[a]anthracene sulfate; 12-Methyl-7-(hydroxymethyl)benz[a]anthracene sulfate ester; 7-Hydroxymethyl-12-methylbenz(a)anthracene sulfate; 7-HM-12-MBA sulfate; 12-Methyl-7-(hydroxymethyl)benzo[a]anthracene sulfuric acid ester; Sulfuric acid, mono[7-(hydroxymethyl)-12-methylbenz[a]anthracen-1-yl] ester; 7-Hydroxymethyl-12-methyl-BA sulfate
EINECS	Contact for details

Quality Control

Our 7-(Hydroxymethyl)-12-Methylbenz(A)Anthracene Sulfate Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials, and custom synthesis and purification to meet specific research-grade specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (-20°C) to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.