Description

1-o-Octadecyl-2-o-Benzyl-Sn-Glycerol is a synthetic glycerol ether derivative with a defined stereochemistry at the Sn position. This compound serves as a crucial intermediate and building block in advanced organic synthesis, particularly for the preparation of complex lipids and phospholipid analogs. It is primarily utilized by pharmaceutical researchers, specialty chemical manufacturers, and R&D laboratories developing novel drug delivery systems, lipid-based formulations, and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of phospholipids, prodrugs, and lipid-conjugated active pharmaceutical ingredients (APIs).
• Lipid Research: Building block for creating structurally defined glycerolipids and ether lipids for biochemical and biophysical studies.
• Drug Delivery Systems: Used in the development of liposomes, niosomes, and other lipid nanoparticle (LNP) components for targeted therapy.
• Specialty Surfactants: Serves as a hydrophobic head-group for synthesizing non-ionic surfactants with specific emulsifying properties.
• Bioconjugation Chemistry: Useful linker molecule for attaching hydrophobic moieties to peptides, proteins, or other biomolecules.
• Material Science: Monomer or modifier for creating functional polymers with lipid-like characteristics.

Basic Information

Product Name	1-o-Octadecyl-2-o-Benzyl-Sn-Glycerol
CAS No.	80707-93-3
Molecular Formula	C28H50O3
Molecular Weight	434.70 g/mol
Synonyms	1-Octadecyl-2-benzyl-sn-glycerol; 1-O-Octadecyl-2-O-benzyl-sn-glycerol; sn-1-Octadecyl-2-benzylglycerol; 2-Benzyl-1-octadecylglycerol; 3-(Benzyloxy)-2-hydroxypropyl octadecyl ether; Glycerol, 1-octadecyl-2-benzyl-, (S)-; Lipid ether intermediate; Benzyl octadecyl glycerol ether
EINECS	Contact for details

Quality Control

Our 1-o-Octadecyl-2-o-Benzyl-Sn-Glycerol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric purity, and impurity profiles are provided and available upon request. We support cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% (Sn-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.