Description

1-Butanol, 4-((1-Nitro-9-Acridinyl)Amino)-, Monohydrochloride is a specialized acridine derivative, a chemical class known for its significant biological activity and utility in advanced research. This compound is valued for its role as a key intermediate or active component in the development of novel therapeutic agents and diagnostic tools. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology, antimicrobials, and molecular biology.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel acridine-based chemotherapeutic agents and antimicrobial drugs.
• Biochemical Research: Used as a fluorescent probe or intercalating agent in nucleic acid binding studies and molecular biology assays.
• Anticancer Agent Development: Investigated for its potential topoisomerase inhibitory activity and DNA-binding properties in oncology research.
• Antiparasitic Drug Synthesis: Acts as a precursor in the development of acridine derivatives targeting trypanosomiasis and other parasitic diseases.
• Diagnostic Reagent Formulation: Employed in the preparation of specialized stains and reagents for cellular and genetic analysis.
• Academic & Contract Research: Utilized in universities and CROs for fundamental studies on drug-DNA interactions and mechanism of action.

Basic Information

Product Name	1-Butanol, 4-((1-Nitro-9-Acridinyl)Amino)-, Monohydrochloride
CAS No.	80704-89-8
Molecular Formula	C21H20N4O3·HCl
Molecular Weight	412.87 g/mol (Free base: 376.41 g/mol)
Synonyms	4-((1-Nitro-9-acridinyl)amino)-1-butanol hydrochloride; 9-Acridinamine, N-(4-hydroxybutyl)-1-nitro-, monohydrochloride; 1-Nitro-9-[(4-hydroxybutyl)amino]acridine hydrochloride; Ledakrin impurity standard (related compound); Nitracrine derivative; C-283 hydrochloride; NSC-382270 (hydrochloride)
EINECS	Contact for details

Quality Control

Our 1-Butanol, 4-((1-Nitro-9-Acridinyl)Amino)-, Monohydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.