Description

D-Norleucinol is a chiral amino alcohol derivative of norleucine, serving as a versatile and high-value building block in advanced organic synthesis. Its significance lies in its role as a key chiral intermediate for constructing complex molecules with precise stereochemistry, which is critical for biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs), peptide mimetics, and chiral ligands.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Peptide Chemistry: Used in the preparation of modified peptides and peptidomimetics to enhance stability, bioavailability, or receptor selectivity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & R&D: A valuable reagent in university and corporate research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	D-Norleucinol
CAS No.	80696-28-2
Molecular Formula	C6H15NO
Molecular Weight	117.19 g/mol
Synonyms	(R)-2-Amino-1-hexanol; (R)-2-Aminohexan-1-ol; D-2-Amino-1-hexanol; (R)-Norleucinol; D-2-Aminohexyl alcohol; (2R)-2-Amino-1-hexanol; (R)-1-Hexanol, 2-amino-; (R)-α-Aminocapryl alcohol
EINECS	Contact for details

Quality Control

Our D-Norleucinol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC/MS, to verify identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.