Description

3-Chloro-4-Ethynylaniline is a high-value aromatic amine building block featuring both chloro and ethynyl substituents, enabling versatile synthetic pathways. This compound is critical for the development of advanced materials and active pharmaceutical ingredients (APIs) due to its unique bifunctional reactivity. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging its halogen and alkyne functionality.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalytic systems.
• Chemical Research: A versatile scaffold for medicinal chemistry, combinatorial library synthesis, and exploring new organic reactions.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and functional colorants.

Basic Information

Product Name	3-Chloro-4-Ethynylaniline
CAS No.	80690-65-9
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	3-Chloro-4-ethynylbenzenamine; 4-Amino-2-chlorophenylacetylene; 2-Chloro-4-aminophenylacetylene; 3-Chloro-4-ethynyl-phenylamine; 1-Amino-2-chloro-4-ethynylbenzene; Benzenamine, 3-chloro-4-ethynyl-; 80690-65-9 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Ethynylaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.