Description

Trt-Met-Oh Dea CAS NO 80514-69-8 is a specialized, protected amino acid derivative widely used as a critical building block in peptide synthesis and pharmaceutical research. Its primary value lies in providing precise stereochemical control and protecting sensitive functional groups during complex multi-step synthetic sequences. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid precursor for the controlled assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for producing custom peptides and peptide fragments.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of peptide-based drugs and APIs.
• Bioconjugation: Employed in the chemical modification of proteins and other biomolecules for drug delivery and diagnostic applications.
• Combinatorial Chemistry: Utilized in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial Research: A fundamental reagent for studying peptide structure, function, and metabolism.

Basic Information

Product Name	Trt-Met-Oh Dea
CAS No.	80514-69-8
Molecular Formula	C27H31NO3S
Molecular Weight	449.61 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-trityl-L-homocysteine; Fmoc-Hcy(Trt)-OH; Fmoc-S-trityl-L-homocysteine; Fmoc-L-homocysteine(S-trityl); N-α-Fmoc-S-trityl-L-homocysteine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-tritylsulfanylbutanoic acid; Fmoc-Hcy(Trt)-OH Dea Salt; Fmoc-S-Trt-L-homocysteine
EINECS	Contact for details

Quality Control

Our Trt-Met-Oh Dea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.