Description

Trityl-L-Alanine Diethylammonium Salt is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound is specifically designed to safeguard the amino functionality during complex peptide coupling and solid-phase peptide synthesis (SPPS) protocols. It is an essential building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, enabling the production of peptides, peptidomimetics, and other bioactive molecules with high precision and yield.

Application

• Peptide Synthesis: A key protected intermediate in the stepwise synthesis of complex peptides, particularly using Fmoc/tBu solid-phase methodologies.
• Pharmaceutical Research: Serves as a crucial building block for the development of novel therapeutic peptides and drug candidates.
• Bioconjugation: Used in the site-specific modification of proteins and other biomolecules where selective protection of the L-alanine residue is required.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery.
• Academic & Industrial R&D: A fundamental reagent for research laboratories focusing on synthetic organic chemistry, medicinal chemistry, and chemical biology.
• Production of Specialty Chemicals: Used in the manufacture of custom amino acid derivatives and fine chemicals with specific chiral requirements.

Basic Information

Product Name	Trityl-L-Alanine Diethylammonium Salt
CAS No.	80514-65-4
Molecular Formula	C24H36N2O2
Molecular Weight	384.56 g/mol
Synonyms	L-Alanine, N-[(triphenylmethyl)-, compd. with N-ethylethanamine (1:1); Trityl-L-Alanine Diethylamine Salt; N-Trityl-L-alanine diethylammonium salt; (S)-2-((Tritylamino)propanoic acid diethylammonium salt; Fmoc SPPS Building Block (related); Nα-Trityl-L-alanine diethylamine salt; N-[(Triphenylmethyl)]-L-alanine diethylammonium salt; Protected L-Alanine derivative.
EINECS	Contact for details

Quality Control

Our Trityl-L-Alanine Diethylammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.