Description

Carboxymethyl Dextran Hydroxamate is a chemically modified polysaccharide derivative designed for advanced bioconjugation and material science applications. This compound matters for its unique ability to chelate metal ions, making it a critical component in the development of targeted drug delivery systems, diagnostic imaging agents, and functionalized hydrogels. It is primarily needed by researchers and manufacturers in the pharmaceutical, biomedical research, and biotechnology industries for creating innovative therapeutic and diagnostic platforms.

Application

• Pharmaceutical Research: As a functional polymer for creating targeted drug conjugates and controlled-release formulations.
• Diagnostic Imaging: Chelation of radionuclides (e.g., Technetium-99m, Gallium-68) for use in SPECT and PET imaging agents.
• Biomaterial Engineering: Modification of surfaces and creation of metal-ion responsive hydrogels for tissue engineering and biosensing.
• Chromatography & Separation Science: Use as a functional ligand in affinity chromatography media for protein purification.
• Cosmetic & Personal Care: Potential use as a bioactive carrier or stabilizer in advanced skincare formulations.
• Industrial Catalysis: Serving as a support matrix for immobilizing metal catalysts in green chemistry processes.

Basic Information

Product Name	Carboxymethyl Dextran Hydroxamate
CAS No.	80451-07-6
Molecular Formula	(C6H10O5)n modified
Molecular Weight	Variable (Depends on dextran backbone and degree of substitution)
Synonyms	CMD-HA; Carboxymethyl Dextran HA; Dextran carboxymethyl ether hydroxamate; Hydroxamic acid derivative of carboxymethyl dextran; Poly(dextran carboxymethyl hydroxamate); CM-Dextran hydroxamate; Dextran, carboxymethyl, hydroxamate
EINECS	Contact for details

Quality Control

Our Carboxymethyl Dextran Hydroxamate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Key parameters monitored include degree of substitution (DS) for both carboxymethyl and hydroxamate groups, molecular weight distribution, and residual solvent levels. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing the results against our internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store the product in a cool, dry place (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Minimize exposure to air and moisture during handling.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Hydroxamate Content)	≥ 85% (by titration)
Degree of Substitution (CM)	0.5 - 2.0 (customizable)
pH (1% solution)	6.0 - 8.0
Loss on Drying	≤ 8.0 %
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.