Description

(R)-(+)-8-Hydroxy-DPAT Hydrobromide is a high-purity, enantiomerically pure chemical compound used as a critical research tool in neuroscience. This compound matters as a potent and selective agonist for the 5-HT1A serotonin receptor, enabling precise pharmacological studies. It is primarily needed by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on neuropharmacology, psychiatric disorders, and receptor signaling pathways.

Application

• Neuroscience Research: A key pharmacological tool for studying the function and distribution of 5-HT1A serotonin receptors in the central nervous system.
• Drug Discovery & Development: Used in high-throughput screening (HTS) and lead optimization for psychiatric and neurological drug candidates targeting serotonin pathways.
• In Vitro & In Vivo Studies: Employed in receptor binding assays, functional studies (e.g., adenylate cyclase inhibition), and behavioral animal models related to anxiety, depression, and cognition.
• Biochemical Standard: Serves as a certified reference standard for analytical method development and validation in pharmacokinetic and metabolic studies.
• Academic & Institutional Research: Fundamental reagent for university labs and research institutes exploring serotonin receptor pharmacology and signal transduction mechanisms.

Basic Information

Product Name	(R)-(+)-8-Hydroxy-DPAT Hydrobromide
CAS No.	80300-09-0
Molecular Formula	C16H25N2O2 • HBr
Molecular Weight	357.30 g/mol
Synonyms	(R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide; (R)-(+)-8-OH-DPAT HBr; (+)-8-Hydroxy-DPAT Hydrobromide; (R)-8-Hydroxy-DPAT HBr; (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin Hydrobromide; 8-Hydroxy-DPAT (R)-(+) isomer Hydrobromide; (R)-8-OH-DPAT HBr
EINECS	Contact for details

Quality Control

Our (R)-(+)-8-Hydroxy-DPAT Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the original container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.