Description

2-Iodoquinoline-3-Carbaldehyde is a versatile and highly functionalized quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of both an iodine atom and an aldehyde group on the quinoline scaffold, enabling a wide range of cross-coupling and condensation reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity building blocks for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for anti-malarial, anti-cancer, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with quinoline-based active ingredients.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other functional organic materials.
• Chemical Biology: Useful as a probe or tagging reagent due to the reactivity of the aldehyde and iodo groups.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis, including Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2-Iodoquinoline-3-Carbaldehyde
CAS No.	80231-40-9
Molecular Formula	C10H6INO
Molecular Weight	283.07 g/mol
Synonyms	3-Formyl-2-iodoquinoline; 2-Iodo-3-quinolinecarboxaldehyde; Quinoline-3-carbaldehyde, 2-iodo-; 2-Iodoquinoline-3-carboxaldehyde; 2-Iodo-3-formylquinoline; 2-Iodo-3-quinolinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Iodoquinoline-3-Carbaldehyde is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere, as the compound is easily oxidized and light-sensitive. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.