Description

n-Dichloroacetyl-L-Serine Sodium Salt is a high-purity, specialized amino acid derivative used as a critical intermediate in advanced chemical synthesis. This compound is valued for its role in the production of complex molecules, particularly in the pharmaceutical sector where precise chirality and purity are paramount. It serves as a key building block for researchers and manufacturers developing novel therapeutic agents, including antibiotics and enzyme inhibitors. Global industries rely on this material for its consistent quality and reliable performance in sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of β-lactam antibiotics and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and enzymology studies as a substrate analog or inhibitor precursor.
• Peptide Synthesis: Serves as a protected serine derivative in solid-phase and solution-phase peptide chemistry.
• Agrochemical Development: Employed in the research and synthesis of novel, targeted crop protection agents.
• Chemical Biology Probes: Utilized to create labeled or modified amino acids for studying biological pathways.
• Reference Standard: Acts as a high-purity certified reference material (CRM) for analytical method development and quality control laboratories.

Basic Information

Product Name	n-Dichloroacetyl-L-Serine Sodium Salt
CAS No.	80174-64-7
Molecular Formula	C5H6Cl2NNaO4
Molecular Weight	238.00 g/mol
Synonyms	L-Serine, N-(dichloroacetyl)-, sodium salt; Sodium N-Dichloroacetyl-L-serinate; (2S)-2-(Dichloroacetamido)-3-hydroxypropanoic acid sodium salt; Dichloroacetylserine Sodium Salt; Serine, N-dichloroacetyl-, sodium salt, L-; 80174-64-7; DCAS-Na
EINECS	Contact for details

Quality Control

Every batch of n-Dichloroacetyl-L-Serine Sodium Salt is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support customer audits and can supply documentation for regulatory submissions as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.