Description

Boc-D-2-Chlorophe CAS NO 80102-23-4 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of D-2-chlorophenylalanine. This high-purity chiral building block is critical for the synthesis of complex peptides and peptidomimetics, where it introduces a chlorinated aromatic side chain with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, bioactive peptides, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-2-chlorophenylalanine residue into peptide chains, enabling structure-activity relationship (SAR) studies.
• Proteomics & Biochemical Research: Serves as a specialized reagent for creating custom peptides, enzyme substrates, or inhibitors in academic and industrial research laboratories.
• Asymmetric Synthesis: Employed in the synthesis of non-natural amino acids and complex organic molecules requiring a stereochemically pure chlorinated aromatic component.
• Material Science: Potential use in the development of specialized polymers or coatings with unique properties derived from its aromatic and halogenated structure.

Basic Information

Product Name	Boc-D-2-Chlorophe CAS NO 80102-23-4
CAS No.	80102-23-4
Molecular Formula	C₁₄H₁₈ClNO₄
Molecular Weight	299.75 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-2-chlorophenylalanine; Boc-D-2-chloro-Phe-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-chlorophenyl)propanoic acid; Boc-D-2-Cl-Phe; D-2-Chlorophenylalanine Boc derivative; N-Boc-D-2-chlorophenylalanine; tert-Butyl (R)-(1-(2-chlorophenyl)-2-carboxyethyl)carbamate; BOC-D-2-CHLORO-PHENYLALANINE
EINECS	Contact for details

Quality Control

Our Boc-D-2-Chlorophe is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >98% by HPLC), specific rotation, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.