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o-Alpha Fucopyranosyl-(1-2)-o-β-Galactopyranosyl-(1-3)-o-(α-Fucopyranosyl)-(1-4)-2-Acetamido-2-Deoxy-Glucopyranose CAS NO 80035-27-4


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CAS No.:80035-27-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

o-Alpha Fucopyranosyl-(1-2)-o-β-Galactopyranosyl-(1-3)-o-(α-Fucopyranosyl)-(1-4)-2-Acetamido-2-Deoxy-Glucopyranose is a complex, well-defined oligosaccharide of significant interest in glycobiology research and development. This compound serves as a critical reference standard and building block for studying carbohydrate-protein interactions, particularly those involving selectins and other lectins. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing novel diagnostics, therapeutics, and vaccines. Its precise structure makes it invaluable for probing biological recognition events and synthesizing more complex glycoconjugates.

Application

  • Glycobiology Research: Used as a high-purity reference standard and probe to study cell-cell recognition, signaling, and adhesion mechanisms.
  • Pharmaceutical Development: Serves as a key intermediate or target molecule in the synthesis of carbohydrate-based drugs, including selectin inhibitors for anti-inflammatory applications.
  • Diagnostic Reagent Production: Employed in the development of diagnostic kits and assays that detect specific carbohydrate-binding proteins or antibodies.
  • Biomarker Studies: Utilized to investigate the role of specific oligosaccharide epitopes as biomarkers for diseases such as cancer.
  • Enzymatic Substrate: Acts as a substrate for glycosyltransferases, glycosidases, and other enzymes involved in carbohydrate metabolism for functional characterization.
  • Vaccine Adjuvant Research: Investigated for its potential immunomodulatory properties in the design of next-generation conjugate vaccines.
  • Synthetic Chemistry: Functions as a sophisticated building block for the chemical and enzymatic synthesis of larger, more complex glycans and neoglycoconjugates.
  • Quality Control: Provides an analytical standard for the quality assurance of related biopharmaceutical products and reagents.

Basic Information

Product Name o-Alpha Fucopyranosyl-(1-2)-o-β-Galactopyranosyl-(1-3)-o-(α-Fucopyranosyl)-(1-4)-2-Acetamido-2-Deoxy-Glucopyranose
CAS No. 80035-27-4
Molecular Formula C32H53NO23
Molecular Weight 843.76 g/mol
Synonyms Fucα1-2Galβ1-3(Fucα1-4)GlcNAc; Lewis a Trisaccharide (Lea); H Type 1 Trisaccharide; Blood Group Antigen Lea Trisaccharide; 2'-Fucosyllactosamine; Galβ1-3(Fucα1-4)GlcNAc with α1-2 linked Fucose; 3-Fucosyl-N-acetyllactosamine derivative; α-L-Fuc-(1→2)-β-D-Gal-(1→3)-[α-L-Fuc-(1→4)]-D-GlcNAc
EINECS Contact for details

Quality Control

Our o-Alpha Fucopyranosyl-(1-2)-o-β-Galactopyranosyl-(1-3)-o-(α-Fucopyranosyl)-(1-4)-2-Acetamido-2-Deoxy-Glucopyranose is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and MS to ensure structural identity and high purity, meeting the exacting standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and consistency for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the product to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (NMR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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