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(R)-(+)-1-(1-Naphthyl)Ethylamine CAS NO 8886-70-2


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CAS No.:8886-70-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(+)-1-(1-Naphthyl)Ethylamine is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile resolving agent and chiral auxiliary for the preparation of enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors where stereochemical control is critical.

Application

  • Chiral Resolving Agent: Widely used for the optical resolution of racemic acids and other chiral compounds via diastereomeric salt formation.
  • Asymmetric Synthesis: Serves as a key chiral auxiliary or ligand in catalytic asymmetric reactions, including hydrogenations and alkylations.
  • Pharmaceutical Intermediates: A critical precursor in the synthesis of enantiopure active pharmaceutical ingredients (APIs) for various therapeutic areas.
  • Agrochemical Synthesis: Employed in the production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
  • Catalyst Development: Used to synthesize novel chiral catalysts and ligands for homogeneous catalysis.
  • Research & Development: A standard reagent in academic and industrial R&D labs for method development in stereoselective chemistry.

Basic Information

Product Name (R)-(+)-1-(1-Naphthyl)Ethylamine
CAS No. 8886-70-2
Molecular Formula C₁₂H₁₃N
Molecular Weight 171.24 g/mol
Synonyms (R)-(+)-1-(1-Naphthyl)ethylamine; (R)-1-(Naphthalen-1-yl)ethan-1-amine; (R)-1-(1-Naphthyl)ethylamine; (+)-(R)-1-(1-Naphthyl)ethylamine; D-1-(1-Naphthyl)ethylamine; (R)-1-(1-Naphthalenyl)ethylamine; (R)-α-Methyl-1-naphthalenemethylamine; (R)-NEA
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Quality Control

Our (R)-(+)-1-(1-Naphthyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, GC, and optical rotation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Enantiomeric Excess (ee) ≥ 99.0%
Optical Rotation [α]²⁰D +40° to +44° (c=1 in ethanol)
Melting Point 48 - 52 °C
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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