Description

2-[[4-(Trifluoromethyl)Phenyl]Thio] Benzoic Acid is a high-value organosulfur compound featuring a benzoic acid core linked to a trifluoromethylphenyl group via a thioether bridge. This unique structure provides a versatile chemical scaffold with significant utility in advanced organic synthesis and materials science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the bioactivity of the trifluoromethyl and thioether motifs.
• Liquid Crystal & OLED Materials: Acts as a precursor or dopant in the production of specialty electronic materials, where its molecular structure can influence charge transport and luminescent properties.
• Polymer Modification: Employed to introduce specific functional groups into polymer chains, enhancing material properties like thermal stability, solubility, or surface characteristics.
• Ligand for Catalysis: Utilized in the design of novel ligands for transition metal catalysts used in cross-coupling and other sophisticated organic transformations.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	2-[[4-(Trifluoromethyl)Phenyl]Thio] Benzoic Acid
CAS No.	895-45-4
Molecular Formula	C14H9F3O2S
Molecular Weight	298.28 g/mol
Synonyms	2-[(4-Trifluoromethylphenyl)sulfanyl]benzoic Acid; 2-((4-(Trifluoromethyl)phenyl)thio)benzoic Acid; Benzoic acid, 2-[[4-(trifluoromethyl)phenyl]thio]-; 2-(p-Trifluoromethylphenylthio)benzoic Acid; α-((4-Trifluoromethylphenyl)thio)benzoic Acid; 2-(4-Trifluoromethylphenylsulfanyl)benzoic Acid; 2-(4-Trifluoromethylphenylmercapto)benzoic Acid
EINECS	Contact for details

Quality Control

Our production of 2-[[4-(Trifluoromethyl)Phenyl]Thio] Benzoic Acid adheres to a stringent quality management system to ensure batch-to-batch consistency and purity for critical R&D and scale-up applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and quantify impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.