Description

3,5-Bis(Trifluoromethyl)Phenylhydrazine is a specialized organofluorine building block featuring a phenylhydrazine core flanked by two trifluoromethyl groups. This compound matters for its unique reactivity as a precursor to heterocyclic compounds and its ability to introduce fluorine-rich motifs, which are critical for modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel compounds with enhanced stability, bioavailability, and performance.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated heterocycles like pyrazoles and indazoles.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Functional Material Research: Employed in the development of advanced organic electronic materials, liquid crystals, and polymers where fluorine content improves thermal and chemical stability.
• Chemical Research & Development: A versatile reagent for constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Phenylhydrazine
CAS No.	886-35-1
Molecular Formula	C8H6F6N2
Molecular Weight	244.14 g/mol
Synonyms	[3,5-Bis(trifluoromethyl)phenyl]hydrazine; 1-[3,5-Bis(trifluoromethyl)phenyl]hydrazine; 3,5-Bis(trifluoromethyl)phenylhydrazine; Hydrazine, [3,5-bis(trifluoromethyl)phenyl]-; 3,5-Bis(trifluoromethyl)benzenamine, N-amino-; α,α,α,α',α',α'-Hexafluoro-3,5-xylylenehydrazine
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Phenylhydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.