Description

2-Chloro-7-Trifluoromethylquinoxaline is a high-value, multi-functional heterocyclic building block characterized by its unique quinoxaline core substituted with chloro and trifluoromethyl groups. This compound matters for its critical role as a versatile intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable electronic and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and fluorescent dyes.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig aminations for C-C and C-N bond formation.
• Ligand and Catalyst Development: Precursor for synthesizing novel chelating ligands and organocatalysts.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-Chloro-7-Trifluoromethylquinoxaline
CAS No.	883-94-3
Molecular Formula	C9H4ClF3N2
Molecular Weight	232.59 g/mol
Synonyms	2-Chloro-7-(trifluoromethyl)quinoxaline; 7-Trifluoromethyl-2-chloroquinoxaline; Quinoxaline, 2-chloro-7-(trifluoromethyl)-; 2-Chloro-7-trifluoromethyl-quinoxaline; 2-Chloro-α,α,α-trifluoro-7-quinoxalinemethanol (related); CTFQ
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Trifluoromethylquinoxaline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), physical characteristics, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.