Description

1H-Indene-1-Carboxylic Acid, 2,3-Dihydro-, (R)- is a high-purity chiral building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined indane carboxylic acid scaffold, which is crucial for constructing complex molecules with specific three-dimensional architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science Research: Employed in the development of chiral polymers, liquid crystals, and other advanced functional materials.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process development.

Basic Information

Product Name	1H-Indene-1-Carboxylic Acid, 2,3-Dihydro-, (R)-
CAS No.	877-01-0
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(R)-2,3-Dihydro-1H-indene-1-carboxylic acid; (R)-1-Indancarboxylic acid; (R)-1,2,3,4-Tetrahydro-1-naphthoic acid; (R)-α,2,3,4-Tetrahydro-1-naphthalenecarboxylic acid; (1R)-2,3-Dihydro-1H-indene-1-carboxylic acid; (R)-(+)-1,2,3,4-Tetrahydro-1-naphthoic acid; (R)-Hydrindene-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of (R)-2,3-Dihydro-1H-indene-1-carboxylic acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure compliance with customer specifications and research-grade standards. A detailed Certificate of Analysis (COA) providing identity, purity, and chiral excess data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.