Description

tert-Butyl Carbazate is a versatile organic compound and a protected derivative of hydrazine, serving as a crucial building block in synthetic chemistry. Its primary value lies in its role as a key reagent for the introduction of the hydrazine moiety under mild conditions, enabling the synthesis of complex molecules. This makes it an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries who require high-purity intermediates for coupling and derivatization reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing hydrazide or carbazate functionalities.
• Peptide Synthesis & Bioconjugation: Used as a protecting group for hydrazine in solid-phase peptide synthesis and for creating stable linkages in antibody-drug conjugates (ADCs).
• Agrochemical Production: Employed in the manufacture of herbicides, fungicides, and plant growth regulators that utilize hydrazine-based chemistries.
• Polymer Chemistry: Acts as a chain extender or cross-linking agent in the production of specialty polymers, polyurethanes, and resins.
• Organic Synthesis Reagent: Facilitates the preparation of hydrazones, semicarbazides, and other nitrogen-containing heterocycles in research and development.
• Corrosion Inhibitor Formulation: A component in formulations designed to protect metal surfaces in industrial processes.

Basic Information

Product Name	tert-Butyl Carbazate
CAS No.	870-46-2
Molecular Formula	C5H12N2O2
Molecular Weight	132.16 g/mol
Synonyms	tert-Butyl Hydrazinecarboxylate; BOC-Hydrazine; N-(tert-Butoxycarbonyl)hydrazine; 1,1-Dimethylethyl Hydrazinecarboxylate; tert-Butoxycarbonyl Hydrazide; Hydrazinecarboxylic Acid tert-Butyl Ester; t-Butyl Carbazate; BOC-NHNH2
EINECS	212-791-8

Quality Control

Our tert-Butyl Carbazate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.