Description

Pentafluorophenylhydrazine is a specialized fluorinated aromatic hydrazine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a perfluorinated phenyl ring, makes it an invaluable reagent for introducing fluorinated moieties, which are essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for creating hydrazone linkages and heterocyclic compounds with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Analytical Chemistry Reagent: Acts as a derivatization agent for the analysis of carbonyl compounds (e.g., aldehydes, ketones) via hydrazone formation in HPLC or LC-MS applications.
• Polymer and Material Science: Serves as a monomer or cross-linking agent for synthesizing fluorinated polymers with unique surface properties, thermal stability, and chemical resistance.
• Research & Development: A versatile tool in academic and industrial R&D for exploring new synthetic pathways and creating fluorinated chemical libraries.

Basic Information

Product Name	Pentafluorophenylhydrazine
CAS No.	828-73-9
Molecular Formula	C6H3F5N2
Molecular Weight	198.10 g/mol
Synonyms	2,3,4,5,6-Pentafluorophenylhydrazine; Pentafluorophenyl Hydrazine; (Pentafluorophenyl)hydrazine; Hydrazine, (pentafluorophenyl)-; Perfluorophenylhydrazine; NSC 404080; F5C6NHNH2
EINECS	Contact for details

Quality Control

Our Pentafluorophenylhydrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to relevant industry standards, and custom purity grades (e.g., >97%, >98%, >99%) are available to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white or light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0 %
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.