Description

1,1,1-Trifluoronitroethane is a versatile fluorinated nitroalkane building block with significant synthetic utility. Its unique structure, featuring both a strong electron-withdrawing nitro group and a trifluoromethyl moiety, makes it a valuable intermediate for introducing fluorine atoms into target molecules. This compound is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors. It serves as a key precursor for the synthesis of more complex fluorinated compounds, including heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated scaffolds in drug discovery and development programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where fluorine substitution enhances biological activity and environmental stability.
• Organic Synthesis Reagent: Employed in nucleophilic substitution, condensation, and cyclization reactions to introduce the -CF3 group.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique surface properties or chemical resistance.
• Fluorine Chemistry Research: Serves as a model compound for studying the reactivity of polyfluorinated nitroalkanes in academic and industrial laboratories.

Basic Information

Product Name	1,1,1-Trifluoronitroethane
CAS No.	819-07-8
Molecular Formula	C2H2F3NO2
Molecular Weight	129.04 g/mol
Synonyms	Nitrotrifluoroethane; Trifluoronitroethane; 1,1,1-Trifluoro-2-nitroethane; 2-Nitro-1,1,1-trifluoroethane; Trifluoromethylnitromethane; FC-113a(N); TFNE; EINECS 212-456-8
EINECS	212-456-8

Quality Control

Our 1,1,1-Trifluoronitroethane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong bases, reducing agents, and open flames. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.45 g/mL
Boiling Point	~ 40-42°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.