Description

5-Bromoisatin is a versatile halogenated isatin derivative, a key heterocyclic building block prized for its reactivity and structural motif. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors, anti-cancer agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocycles like indoles, quinolones, and spirooxindoles via cross-coupling and condensation reactions.
• Material Science Research: Employed in the development of organic semiconductors, dyes, and photoactive materials.
• Bioconjugation & Probe Development: Useful for modifying biomolecules and creating fluorescent or reactive probes for biochemical assays.

Basic Information

Product Name	5-Bromoisatin
CAS No.	87-48-9
Molecular Formula	C8H4BrNO2
Molecular Weight	226.03 g/mol
Synonyms	5-Bromo-1H-indole-2,3-dione; 5-Bromo-2,3-dihydroxyindole; 5-Bromo-2,3-indolinedione; 5-Bromoisatin; 5-Bromooxindole; Isatin, 5-bromo-; 5-Bromoindole-2,3-dione
EINECS	201-751-5

Quality Control

Our 5-Bromoisatin is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.