Description

4-Bromo Phthalic Anhydride (CAS NO 86-90-8) is a versatile halogenated aromatic anhydride that serves as a critical building block in advanced organic synthesis. Its value lies in its reactive anhydride group and bromine substituent, enabling precise functionalization for creating complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring brominated aromatic cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the bromo-phthalimide structure imparts specific biological activity.
• Polymer & Resin Modifier: Incorporated into polyimide, polyester, and epoxy resins to enhance flame retardancy, thermal stability, and mechanical properties.
• Dye & Pigment Manufacturing: Serves as a starting material for synthesizing brominated phthalocyanine dyes and other high-value colorants.
• Liquid Crystal & OLED Materials: A crucial building block for creating brominated aromatic components used in electronic display technologies.
• Organic Synthesis Reagent: Employed in laboratories for Friedel-Crafts acylation, imide formation, and other reactions to introduce functionalized phthalic groups.

Basic Information

Product Name	4-Bromo Phthalic Anhydride
CAS No.	86-90-8
Molecular Formula	C8H3BrO3
Molecular Weight	227.01 g/mol
Synonyms	4-Bromophthalic Anhydride; 5-Bromoisobenzofuran-1,3-dione; 4-Bromophthalic Acid Anhydride; 5-Bromo-1,3-dihydroisobenzofuran-1,3-dione; 4-BPA; NSC 403107; 1,3-Dioxo-5-bromo-1,3-dihydro-2-benzofuran; Bromophthalic Anhydride (4-isomer)
EINECS	201-713-0

Quality Control

Our 4-Bromo Phthalic Anhydride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets exacting specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	114 - 118 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.