Description

4-Chlorophthalic Anhydride is a versatile halogenated aromatic anhydride, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, enabling the creation of complex molecules with tailored properties for high-performance applications. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex aromatic backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where the chlorinated aromatic ring enhances biological activity.
• Polymer & Resin Modifiers: Acts as a monomer or curing agent in the manufacture of high-temperature resistant polyimides, epoxy resins, and other specialty polymers.
• Dye & Pigment Manufacturing: Serves as an intermediate for producing chlorinated phthalocyanine dyes and other complex colorants.
• Liquid Crystal & OLED Materials: Employed in the synthesis of organic electronic materials due to its ability to modify electronic and structural properties.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing biaryl structures.

Basic Information

Product Name	4-Chlorophthalic Anhydride
CAS No.	118-45-6
Molecular Formula	C8H3ClO3
Molecular Weight	182.56 g/mol
Synonyms	4-Chloro-1,3-dihydro-1,3-dioxoisobenzofuran; 4-Chlorophthalic Acid Anhydride; 1,3-Dioxo-1,3-dihydroisobenzofuran-4-carbonyl chloride (misnomer); 4-Chloroisobenzofuran-1,3-dione; 4-Chloro-1,3-isobenzofurandione; 4-CPA; Chlorophthalic Anhydride; NSC 403107
EINECS	204-254-7

Quality Control

Our 4-Chlorophthalic Anhydride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for critical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.