Description

8-Quinolineboronic Acid is a versatile organoboron compound widely used as a key building block in modern synthetic chemistry. Its primary value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex quinoline-based drug candidates and active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for palladium-catalyzed C-C bond formation to create biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with quinoline scaffolds.
• Material Science Research: Employed in the creation of organic ligands for catalysis, organic light-emitting diodes (OLEDs), and other functional organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biological target identification and validation.
• Custom Synthesis & Scale-up: A fundamental starting material for contract research organizations (CROs) and custom synthesis manufacturers.

Basic Information

Product Name	8-Quinolineboronic Acid
CAS No.	86-58-8
Molecular Formula	C9H8BNO2
Molecular Weight	173.98 g/mol
Synonyms	8-Quinolylboronic Acid; Quinolin-8-ylboronic Acid; (8-Quinolinyl)boronic Acid; 8-Boronquinoline; 8-Quinoline Boronic Acid; 8-Quinolyl-B(OH)2; 8-Quinolineboric Acid
EINECS	Contact for details

Quality Control

Our 8-Quinolineboronic Acid is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.