Description

3-[(2R)-2-Hydroxy-3-Methyl-Butyl]-4,8-Dimethoxy-1-Methyl-Quinolin-2-On E is a high-purity, chiral quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and chiral intermediate for the development of complex pharmaceutical molecules and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry and high purity are paramount for efficacy and process reliability.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Research: Used in the development of advanced crop protection agents and pesticides, leveraging its complex molecular structure for enhanced biological activity.
• Fine Chemical Synthesis: Employed as a sophisticated building block in multi-step organic synthesis for creating complex natural product analogs and specialty materials.
• Asymmetric Catalysis Studies: Serves as a substrate or ligand precursor in the development and testing of new asymmetric catalytic systems.
• Biochemical Research: Utilized in academic and industrial research to study enzyme interactions and develop enzyme inhibitors due to its quinoline core structure.

Basic Information

Product Name	3-[(2R)-2-Hydroxy-3-Methyl-Butyl]-4,8-Dimethoxy-1-Methyl-Quinolin-2-On E
CAS No.	83-58-9
Molecular Formula	C₁₇H₂₃NO₄
Molecular Weight	305.37 g/mol
Synonyms	2(1H)-Quinolinone, 3-[(2R)-2-hydroxy-3-methylbutyl]-4,8-dimethoxy-1-methyl-; (R)-3-(2-Hydroxy-3-methylbutyl)-4,8-dimethoxy-1-methylquinolin-2(1H)-one; 4,8-Dimethoxy-1-methyl-3-[(2R)-2-hydroxy-3-methylbutyl]quinolin-2(1H)-one; 3-[(2R)-2-Hydroxy-3-methylbutyl]-4,8-dimethoxy-1-methyl-2(1H)-quinolinone; CAS 83-58-9
EINECS	Contact for details

Quality Control

Every batch of 3-[(2R)-2-Hydroxy-3-Methyl-Butyl]-4,8-Dimethoxy-1-Methyl-Quinolin-2-On E is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting industry standards for research and production. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (R-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.