Description

[2R,(-)]-3,9-Dihydro-8-Methoxy-9-Methyl-2-Isopropylfuro[2,3-B]Quinoline-4(2H)-One is a high-purity, chiral furoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate or a key scaffold for developing novel bioactive molecules, particularly in medicinal chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or study structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) or anti-infective agents.
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing novel compounds to explore new biological targets and pathways.
• Asymmetric Synthesis: Employed in chiral synthesis due to its defined stereochemistry at the 2-position, useful for creating enantiomerically pure products.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Agrochemical Research: Investigated as a precursor for developing new crop protection agents with specific modes of action.

Basic Information

Product Name	[2R,(-)]-3,9-Dihydro-8-Methoxy-9-Methyl-2-Isopropylfuro[2,3-B]Quinoline-4(2H)-One
CAS No.	82-40-6
Molecular Formula	C₁₆H₁₇NO₃
Molecular Weight	271.31 g/mol
Synonyms	(-)-Cuspareine; (R)-(-)-Cuspareine; 2R-Cuspareine; (2R)-3,9-Dihydro-8-methoxy-9-methyl-2-(propan-2-yl)furo[2,3-b]quinolin-4-one; 2-Isopropyl-8-methoxy-9-methylfuro[2,3-b]quinolin-4(9H)-one; Furo[2,3-b]quinoline-4(2H)-one, 3,9-dihydro-8-methoxy-9-methyl-2-(1-methylethyl)-, (2R)-; Cuspareine
EINECS	Contact for details

Quality Control

Our [2R,(-)]-3,9-Dihydro-8-Methoxy-9-Methyl-2-Isopropylfuro[2,3-B]Quinoline-4(2H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP standards for pharmaceutical applications, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]₂₀ᴰ	Contact for details
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.