Description

2-Sulfobenzoic Anhydride is a versatile and reactive organic intermediate, primarily valued for its role as a key building block in the synthesis of more complex molecules. Its significance lies in its ability to introduce sulfonic acid functionality, which is crucial for modifying solubility, stability, and biological activity in target compounds. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sulfonamide or sulfonate ester groups.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the sulfonyl moiety enhances efficacy and environmental profile.
• Dye and Pigment Manufacturing: Serves as a key intermediate for creating sulfonated dyes, which offer excellent water solubility and fiber affinity.
• Polymer Modification: Employed to introduce sulfonic acid groups into polymers, improving characteristics like hydrophilicity, ion-exchange capacity, or adhesion properties.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing heterocyclic compounds and other complex molecular architectures.
• Surfactant and Detergent Industry: Acts as a building block for anionic surfactants due to its potential to form sulfonate salts.

Basic Information

Product Name	2-Sulfobenzoic Anhydride
CAS No.	81-08-3
Molecular Formula	C7H4O4S
Molecular Weight	184.17 g/mol
Synonyms	Benzoic acid, 2-sulfo-, cyclic anhydride; 2-Sulfobenzoic acid cyclic anhydride; o-Sulfobenzoic anhydride; 1,3-Dihydro-1,3-dioxo-2,1-benzoxathiole; 2,1-Benzoxathiol-3-one, 1,1-dioxide; Saccharin intermediate; Saccharin anhydride; o-Carboxybenzenesulfonic anhydride
EINECS	201-322-2

Quality Control

Our 2-Sulfobenzoic Anhydride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	128°C - 132°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.