Description

(S)-1-(2-Piperidino-Phenyl)-3-Methyl-1-Butyl-n-4-Methoxybenzyl-Ammonium L-Mandelate is a high-purity, chiral ammonium salt mandelate derivative of significant interest in advanced pharmaceutical synthesis. This compound matters as a critical chiral intermediate or resolving agent for the development of enantiomerically pure active pharmaceutical ingredients (APIs), where stereochemical control is paramount. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.

Application

• Chiral Intermediate in API Synthesis: Serves as a key building block for the production of enantiomerically pure pharmaceutical compounds.
• Asymmetric Resolution Agent: Used in the optical resolution of racemic mixtures to isolate desired enantiomers.
• Pharmaceutical Research & Development: A valuable tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard for method development and quality control in chiral analysis (e.g., HPLC, SFC).
• Catalyst or Ligand Precursor: Potential use in the synthesis of chiral catalysts or ligands for asymmetric transformations.
• Neurological & Cardiovascular Drug Development: Relevant for synthesizing compounds targeting receptors where the piperidino-phenyl moiety is pharmacologically active.

Basic Information

Item	Details
Product Name	(S)-1-(2-Piperidino-Phenyl)-3-Methyl-1-Butyl-n-4-Methoxybenzyl-Ammonium L-Mandelate
CAS No.	799255-55-3
Molecular Formula	C31H46N2O4
Molecular Weight	510.72 g/mol
Synonyms	(S)-1-(2-Piperidinophenyl)-3-methyl-1-butyl-n-4-methoxybenzylammonium L-mandelate; (S)-1-(2-Piperidinylphenyl)-3-methylbutyl(4-methoxybenzyl)ammonium (R)-2-hydroxy-2-phenylacetate; L-Mandelic acid salt of (S)-1-(2-Piperidino-Phenyl)-3-Methyl-1-Butyl-n-4-Methoxybenzyl-Ammonium; (S)-1-(2-Piperidinophenyl)-3-methyl-1-butyl(4-methoxybenzyl)ammonium (R)-mandelate; CAS 799255-55-3; Ammonium, (1S)-1-(2-piperidinylphenyl)-3-methylbutyl(4-methoxyphenyl)methyl-, (R)-2-hydroxy-2-phenylacetate
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Piperidino-Phenyl)-3-Methyl-1-Butyl-n-4-Methoxybenzyl-Ammonium L-Mandelate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and cGMP-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.