Description

6(5H)-Phenanthridinone,6A,10A-Dihydro-5,8-Dimethyl-,(6Ar,10As)-Rel-(9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This specialized chemical serves as a critical chiral building block and intermediate for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-cancer targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Natural Product Synthesis: Serves as a building block for the total synthesis of alkaloids and other complex natural products containing the phenanthridine core.
• Chemical Biology Probes: Utilized in the development of fluorescent tags or molecular probes for studying biological systems and mechanisms.
• Process Chemistry Development: Investigated for scalable synthetic routes in the optimization and manufacturing of advanced intermediates.

Basic Information

Product Name	6(5H)-Phenanthridinone,6A,10A-Dihydro-5,8-Dimethyl-,(6Ar,10As)-Rel-(9Ci)
CAS No.	797762-40-4
Molecular Formula	C15H15NO
Molecular Weight	225.29 g/mol
Synonyms	(6aR,10aS)-6a,10a-Dihydro-5,8-dimethyl-6(5H)-phenanthridinone; rel-(6aR,10aS)-6a,10a-Dihydro-5,8-dimethyl-6(5H)-phenanthridinone; 6(5H)-Phenanthridinone, 6a,10a-dihydro-5,8-dimethyl-, (6aR,10aS)-rel-; 797762-40-4; (rel-6aR,10aS)-5,8-Dimethyl-6a,10a-dihydro-6H-phenanthridin-6-one
EINECS	Contact for details

Quality Control

Our 6(5H)-Phenanthridinone,6A,10A-Dihydro-5,8-Dimethyl-,(6Ar,10As)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity assessment, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.