Description

Urea, n-(2-Fluoro-5-Methylphenyl)-N'-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a specialized organic compound that serves as a critical pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent. Its molecular architecture, featuring a urea linkage and a boronic ester pinacol group, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic ester reagent for forming carbon-carbon bonds in medicinal chemistry and materials science.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Potential intermediate in the synthesis of functional materials for organic light-emitting diodes (OLEDs) or semiconductors.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	Urea, n-(2-Fluoro-5-Methylphenyl)-N'-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	796967-18-5
Molecular Formula	C20H24BFN2O3
Molecular Weight	370.23 g/mol
Synonyms	1-(2-Fluoro-5-methylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-(2-Fluoro-5-methylphenyl)-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl (2-fluoro-5-methylphenyl)carbamate (related precursor); (4-(3-(2-Fluoro-5-methylphenyl)ureido)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our high-purity Urea derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.