Description

5-Chloro-4-(Trifluoromethyl)Nicotinic Acid is a high-value, multi-functional chemical building block characterized by its unique trifluoromethyl and chloro-substituted pyridine core. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts critical properties like metabolic stability and enhanced bioactivity. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides and fungicides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Research: Used in the synthesis of functionalized ligands and metal-organic frameworks (MOFs) for catalytic and sensing applications.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing complex, fluorinated organic molecules.
• Biochemical Tool Compound: Utilized in life sciences research as a probe or inhibitor to study biological pathways and enzyme functions.

Basic Information

Product Name	5-Chloro-4-(Trifluoromethyl)Nicotinic Acid
CAS No.	796090-28-3
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	5-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-chloro-4-(trifluoromethyl)-; 5-Chloro-4-trifluoromethylnicotinic acid; 796090-28-3; 5-Chloro-4-(trifluoromethyl)nicotinate
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-4-(Trifluoromethyl)Nicotinic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemicals. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.