Description

N1-(2,2-Difluoroethyl)-N1-Methyl-1,2-Ethanediamine is a specialized organic building block featuring a difluoroethyl group and a methylated diamine backbone. This compound matters as a high-value intermediate for synthesizing complex molecules, particularly in pharmaceutical research where its fluorine atoms can enhance metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for oncology and central nervous system (CNS) therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides where the fluorine moiety improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, adhesion, or fluorinated characteristics.
• Chemical Biology Probes: Utilized in the synthesis of fluorescent tags or molecular probes for studying biological mechanisms.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	N1-(2,2-Difluoroethyl)-N1-Methyl-1,2-Ethanediamine
CAS No.	795299-76-2
Molecular Formula	C5H12F2N2
Molecular Weight	138.16 g/mol
Synonyms	1,2-Ethanediamine, N1-(2,2-difluoroethyl)-N1-methyl-; N-Methyl-N-(2,2-difluoroethyl)ethylenediamine; 2,2-Difluoro-N-methylethane-1,1-diamine; N1-(2,2-Difluoroethyl)-N1-methylethane-1,2-diamine; N-Methyl-N-(2,2-difluoroethyl)-1,2-ethanediamine; (2,2-Difluoroethyl)(methyl)aminoethylamine; N-(2,2-Difluoroethyl)-N-methylethylenediamine
EINECS	Contact for details

Quality Control

Our N1-(2,2-Difluoroethyl)-N1-Methyl-1,2-Ethanediamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.