Description

(S)-Bay 73-6691 is a high-purity, enantiomerically pure chemical compound identified by CAS NO 794568-91-5. This compound is a potent and selective inhibitor of phosphodiesterase 1 (PDE1), making it a critical research tool for investigating cognitive function and neurological pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in neuroscience and drug discovery. Its specific stereochemistry is essential for targeted biological activity in preclinical studies.

Application

• Neuroscience Research: As a selective PDE1 inhibitor for studying cognitive enhancement, memory formation, and learning processes in preclinical models.
• Drug Discovery & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel central nervous system (CNS) therapeutics.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro enzymatic assays to evaluate PDE1 inhibition and selectivity profiles.
• Pharmacology Studies: Employed to investigate the role of cyclic nucleotide signaling in various disease models, including neurodegenerative disorders.
• Academic Research: A vital reagent for universities and research institutes focusing on molecular neurobiology and signal transduction pathways.

Basic Information

Product Name	(S)-Bay 73-6691
CAS No.	794568-91-5
Molecular Formula	C₂₀H₂₀ClN₃O₃
Molecular Weight	385.84 g/mol
Synonyms	(S)-1-(4-Chlorophenyl)-6,7-dimethoxy-3-methyl-3,4-dihydro-1H-isoquinoline-2,8-dione; (S)-BAY 73-6691; (S)-1-(4-Chloro-phenyl)-6,7-dimethoxy-3-methyl-1,4-dihydro-isoquinoline-2,8-dione; BAY-73-6691 (S-enantiomer); PDE1 Inhibitor (S)-BAY 73-6691; (S)-Enantiomer of BAY 73-6691
EINECS	Contact for details

Quality Control

Our (S)-Bay 73-6691 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR, and mass spectrometry for structural confirmation, to ensure compliance with research-grade standards. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment to guarantee reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.