Description

3-Ethynylpiperidine is a versatile alkyne-functionalized piperidine derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in the unique reactivity of the terminal alkyne group, which enables efficient coupling reactions and cycloadditions for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, including kinase inhibitors, CNS-active compounds, and other bioactive molecules.
• Agrochemical Research: Used in creating advanced pesticide and herbicide scaffolds with improved efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, dendrimers, and smart materials.
• Chemical Synthesis: Employed in Click Chemistry (e.g., Copper-Catalyzed Azide-Alkyne Cycloaddition) and Sonogashira coupling reactions for efficient carbon-carbon bond formation.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	3-Ethynylpiperidine
CAS No.	794533-54-3
Molecular Formula	C7H11N
Molecular Weight	109.17 g/mol
Synonyms	3-Ethynylpiperidine; 3-Piperidinylacetylene; 1-(2-Propynyl)piperidine; Piperidine, 3-ethynyl-; 3-(Piperidin-3-yl)acetylene; 3-Ethynyl-piperidine; 3-Piperidin-3-ylacetylene; 794533-54-3
EINECS	Contact for details

Quality Control

Our 3-Ethynylpiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR results, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring suitability for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.