Description

5-Methoxy-7-Trifluoromethyl-1,2,3,4-Tetrahydro-[2,6]Naphthyridine is a high-value, multi-functional heterocyclic building block characterized by its naphthyridine core and strategically positioned methoxy and trifluoromethyl substituents. This compound is essential for advanced research and development, particularly in the synthesis of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new drug candidates, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the research and synthesis of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Acts as a precursor for the synthesis of advanced organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology & Proteomics: Employed as a versatile building block for creating molecular probes and tool compounds to study biological pathways and enzyme functions.
• Medicinal Chemistry Library Synthesis: A key component for constructing diverse compound libraries for high-throughput screening (HTS) in drug discovery campaigns.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and complex intermediates under cGMP conditions.

Basic Information

Product Name	5-Methoxy-7-Trifluoromethyl-1,2,3,4-Tetrahydro-[2,6]Naphthyridine
CAS No.	794461-83-9
Molecular Formula	C11H11F3N2O
Molecular Weight	244.21 g/mol
Synonyms	5-Methoxy-7-(trifluoromethyl)-1,2,3,4-tetrahydro-2,6-naphthyridine; 7-Trifluoromethyl-5-methoxy-1,2,3,4-tetrahydro-2,6-naphthyridine; 1,2,3,4-Tetrahydro-5-methoxy-7-(trifluoromethyl)-2,6-naphthyridine; 794461-83-9; 5-Methoxy-7-trifluoromethyl-1,2,3,4-tetrahydro[2,6]naphthyridine; 5-Methoxy-7-trifluoromethyl-1,2,3,4-tetrahydro-2,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 5-Methoxy-7-Trifluoromethyl-1,2,3,4-Tetrahydro-[2,6]Naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications from research to pre-clinical development, with the capability to supply material meeting higher purity standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.