Description

2H-Pyrano[2,3-F]Quinolin-3-Amine,3,4-Dihydro-,(3R)-(9Ci) is a high-purity, chiral heterocyclic amine building block of significant interest in advanced organic synthesis. Its complex fused pyranoquinoline structure makes it a valuable precursor for the development of novel pharmacologically active compounds. This material is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, anti-infectives, or oncology.
• Medicinal Chemistry Research: Used as a privileged structure for constructing compound libraries in high-throughput screening (HTS) to identify new biological activity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, leveraging its amine functionality and rigid polycyclic framework for further functionalization.
• Asymmetric Catalysis Studies: Acts as a chiral ligand precursor or a substrate in the development and testing of new asymmetric synthetic methodologies.
• Agrochemical Research: Investigated as an intermediate for novel crop protection agents due to its heterocyclic architecture.
• Material Science Precursor: Potential use in synthesizing organic semiconductors or fluorescent dyes due to the extended conjugated system of the quinoline core.

Basic Information

Product Name	2H-Pyrano[2,3-F]Quinolin-3-Amine,3,4-Dihydro-,(3R)-(9Ci)
CAS No.	793671-30-4
Molecular Formula	C₁₂H₁₂N₂O
Molecular Weight	200.24 g/mol
Synonyms	(3R)-3,4-Dihydro-2H-pyrano[2,3-f]quinolin-3-amine; (R)-3-Amino-3,4-dihydro-2H-pyrano[2,3-f]quinoline; 2H-Pyrano[2,3-f]quinolin-3-amine, 3,4-dihydro-, (3R)-; (3R)-3,4-Dihydro-2H-pyrano[2,3-f]quinolin-3-ylamine; (R)-3,4-Dihydro-2H-pyrano[2,3-f]quinolin-3-amine; 793671-30-4; (R)-enantiomer of DHPAQ; Chiral pyranoquinoline amine
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyrano[2,3-F]Quinolin-3-Amine,3,4-Dihydro-,(3R)-(9Ci) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and chiral integrity. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and identification data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.